STI diagnoses rose five per cent from 448,422 to 428.255 in England in 2012.
The high rates indicate people continue to risk infection through unsafe sex, especially young adults and men who have sex with men.
In a joint statement, sexual health charities Brook and FPA said: 'It appears from the rise in STI diagnoses among many groups of people, regardless of their sexual preference, that condom use is on the wane.'
They urged ministers to renew national campaigns around condom use 'with vigour'.
Chlamydia is the most commonly diagnosed STI (46 per cent), while new gonorrhoea diagnoses rose by 21 per cent. Tackling the spread of resistant strains of gonorrhoea remains a public health priority.