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No benefit to double doses of flu antivirals

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There are no virological or clinical benefits to giving double doses of the drug oseltamivir to patients with influenza, according to a study published online by bmj.com.

Researchers at the South East Asian Infectious Disease Clinical Research Network studied 326 patients who received either standard dose oseltamivir (75 mg twice a day or children's equivalent) or double dose (150 mg twice a day or children's equivalent) for five days.

The researchers found no differences between the groups in virus levels, deaths or rates of adverse events between the different doses.

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