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Glaucoma, coffee and smoking

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Coffee increases glaucoma risk
Invest Opthalmol Vis Sci (2012) 53:6427-33

Drinking at least three cups of caffeinated coffee a day increases the risk of developing glaucoma, according to a study reported in Investigative Opthalmology and Visual Science.

Researchers monitored 78,977 women and 41,202 men between 1980 and 1986 to 2008. Drinking at least three cups of caffeinated coffee a day increased risk of confirmed/suspected exfoliation glaucoma (cellular debris blocks the trabecular meshwork, through which fluid drains from the eye) by 66 per cent (relative risk [RR] 1.66), when compared with those who drank no caffeinated coffee. Here, 21 per cent of women and 12 per cent of men drank at three cups of caffeinated coffee daily.

Relative risk of exfoliation glaucoma in those drinking at least three cups of caffeinated coffee a day was more marked in women with a family history of glaucoma (RR 2.93) than in those without (RR 1.32 - not significant).

Vitamin supplements cut cancer risk
JAMA (2012) doi:10.1001/jama. 2012.14641

Taking a daily multivitamin supplement 'modestly' reduces cancer risk, according to a randomised, double-blind trial that enrolled 14 641 US men aged at least 50 years.

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