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Menopause, cancer and stress

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Early menopause doubles the risk of CVD and stroke
Menopause (2012) 19:1081-1087

Early menopause doubles the risk of cardiovascular disease (CVD) and stroke, according to American research that enrolled 2,509 women, age 45 to 84 years, from white, Chinese, black and Hispanic backgrounds. A total of 28 per cent underwent menopause, either naturally or following surgical removal of their ovaries, before 46 years of age.

Over the median 4.8-year follow up and after adjusting for age, race and ethnicity, study site and traditional CVD risk factors, women who underwent early menopause were around twice as likely to develop coronary heart disease (CHD) (hazard ratio 2.08) and stroke (HR 2.19) as controls.

Therefore, preventing early menopause - such as by avoiding oophorectomy and tackling smoking - 'may have significant public health relevance for the prevention of CVD in women'.

Asthma may be linked to irregular periods
Am J Epidemiol (2012) doi:10.1093/aje/kws161

Irregular menstruation may increase the risk of developing atopic ('allergic') asthma and atopy, researchers from the University of Bristol report.


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