Inappropriate prescribing common among the elderly
Int J Pharm Pract (2013) 21 (suppl 2):12-3 doi: 10.1111/ijpp.12063
Almost 30% of older people in the UK may be taking potentially inappropriate prescription (PIP) medicines, a study of treatments received by 1,019,491 patients aged at least 70 years suggested. Overall, 29% of patients met PIP criteria, usually for: therapeutic duplication (11.93%); aspirin without a history of coronary, cerebral or peripheral vascular symptoms or occlusive arterial event (11.34%); and taking the maximum therapeutic dose of proton pump inhibitors for more than eight weeks (3.74%).
The study revealed that poly- pharmacy increased PIP risk: 14.58% of patients were prescribed one potentially inappropriate medication, while 7.64% and 6.78% received two and three or more, respectively. Patients receiving at least four different medications were 17.87 times more likely to meet PIP criteria than those receiving up to three medications.
Obesity increases migraine risk
Neurology (2013) doi: 10.1212/WNL.0b013e3182a824f7