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Clinical

Recognising prediabetes

Management
Prediabetes identifies a cohort of patients at high risk of progression to diabetes, says David Morris

Prediabetes is a term that embraces various states of hyperglycaemia that fall short of reaching the criteria for diabetes.

The condition encompasses impaired fasting glucose and impaired glucose tolerance, and some clinicians would also include gestational diabetes.

In part, the term has arisen because of the shift in diagnostic testing preference from fasting glucose and oral glucose tolerance tests to using glycated haemoglobin (HbA1c).

The usual evolution of type 2 diabetes is from normoglycaemia through prediabetes to a formal diagnosis of diabetes. Progression is not, however, inevitable and for this reason the term prediabetes has been said to be misleading. Alternative terms have been proposed, including intermediate hyperglycaemia, impaired glucose regulation, and, the RCGP favoured term, non-diabetic hyperglycaemia.1

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