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Statins, psoriasis, AED abuse

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Statins increase herpes zoster risk

Clinical Infectious Diseases (2013) doi: 10.1093/cid/cit745

Statins may trigger around one-in-ten cases of herpes zoster in older people, according to Canadian researchers who retrospectively reviewed 494,651 patients treated with a statin and an equal number of untreated people aged at least 66 years. The rate of herpes zoster was 13% higher among users of statins than non-users (13.25 and 11.71 per 1000 person-years, respectively). Among people with diabetes, the rate of herpes zoster was 18% higher among statins users than non-users.

The authors estimated that not prescribing statins would have avoided 11.6% of the episodes of herpes zoster among older people. Further research should clarify the mechanisms through which statins reactivate Varicella zoster virus and whether younger patients are at risk.

Weight loss improves psoriasis

British Journal of Dermatology (2031) doi: 10.1111/bjd.12735

Rheumatology (2013) doi: 10.1093/rheumatology/ket343

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