This site is intended for healthcare professionals only

HRT may reduce CV risk if started early

Written by: | Published:

Women taking HRT for 10 years after menopause have a 'significantly reduced' risk of mortality, heart failure and heart attack without increased risk of cancer, DVT or stroke, a study by the BMJ suggests.

Researchers in Denmark carried out a randomised trial over 16 years, to establish if HRT can reduce cardiovascular (CV) risk if started early. A sample of 1,006 women (504 on HRT; 502 not on HRT) was included All participants were white, healthy, recently menopausal and age 45-58.

After 10 years of randomised treatment, patients were encouraged to discontinue HRT. During this period, 26 women in the non-HRT group died and 33 died or experienced a CV end-point, compared to 15 deaths and 16 deaths or CV end-points in the HRT group.

In the subsequent six years, the primary end-point was seen in 53 women in the non-HRT group (40 deaths, eight heart failures and five heart attacks) and 33 in the HRT group (27 deaths, three heart failures and three heart attacks).

Causes of death were 23 CV deaths and 17 non-CV deaths in the non-HRT group and six CV deaths and 21 non-CV deaths in the HRT group.

What do you think? Leave a comment below or tweet your views to @IndyNurseMag

This material is protected by MA Healthcare Ltd copyright.
See Terms and Conditions.



Please view our Terms and Conditions before leaving a comment.

Change the CAPTCHA codeSpeak the CAPTCHA code

Read a free issue from Practice Nursing

Register to read a free issue from our sister publication, Practice Nursing.

Including articles on asthma, diabetes and more. Read your copy.


Sign up to the newsletter


Independent Nurse is the professional resource for primary care and community nurses, providing clinical articles for practice nurses and prescribers.


Subscribe to our newsletter and stay up to date with the latest nursing news.

Stay Connected

Stay social with Independent Nurse by following us on Twitter, liking us on Facebook or connecting on LinkedIn.


Need access to some of our older articles? You can view our archive, or alternatively contact us.

Contact Us

MA Healthcare Ltd.
St Jude's Church, Dulwich Road
London, SE24 0PB

Tel: +44 (0)20 7738 5454
Registered in England and Wales No. 01878373

Meet the team


Find out how to contribute to Independent Nurse here.