This site is intended for healthcare professionals only

Vaccines and paediatric ADRs

Written by: | Published:

Br J Clin Pharmacol 2012;73:437-446

Vaccines are the therapeutic class most commonly linked to paediatric adverse drug reactions (ADR), according to an analysis of Yellow Cards. The study also found that ADR reporting by nurses increased dramatically in recent years.

On average, the MHRA receives 2,146 ADR reports a year concerning children, around 14 per cent of yellow cards. Between 2000-2009, reports mentioned 18 vaccines and 152 medicines. Headache (10 per cent), dizziness (9.3 per cent) and pyrexia (7 per cent) were the most frequently reported symptoms.

Vaccines were included in 66.5 per cent of paediatric ADR reports, reflecting their 'high usage compared with medicines'. Meningococcal Serogroup C conjugate was the most frequently implicated vaccine (38.2 per cent of Yellow Cards), followed by HPV (7.8 per cent) and BCG (4.1 per cent).
Methylphenidate (2.1 per cent), atomoxetine (1.5 per cent) and valproic acid (0.8 per cent) were the most commonly reported drugs.

The proportion of Yellow Cards completed by nurses rose from 23.5 per cent of paediatric ADRs in 2001 to 41.8 per cent in 2009. Reporting by doctors and pharmacy teams remained comparatively constant.

What do you think? Leave a comment below or tweet your views to @IndyNurseMag

This material is protected by MA Healthcare Ltd copyright.
See Terms and Conditions.

Comments

Name
 
Email
 
Comments
 

Please view our Terms and Conditions before leaving a comment.

Change the CAPTCHA codeSpeak the CAPTCHA code
 

Most read articles from Practice Nursing Journal

Practice Nursing Journal latest issue and most read articles.

Click here to read a selection of free to access articles from Practice Nursing Journal

Newsletter

Sign up to the newsletter

About

Independent Nurse is the professional resource for primary care and community nurses, providing clinical articles for practice nurses and prescribers.

Newsletter

Subscribe to our newsletter and stay up to date with the latest nursing news.

Stay Connected

Stay social with Independent Nurse by following us on Twitter, liking us on Facebook or connecting on LinkedIn.

Archive

Need access to some of our older articles? You can view our archive, or alternatively contact us.

Contact Us

MA Healthcare Ltd.
St Jude's Church, Dulwich Road
London, SE24 0PB

Tel: +44 (0)20 7738 5454
Registered in England and Wales No. 01878373

Meet the team

Authors

Find out how to contribute to Independent Nurse here.